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Journal Articles

Isotopic composition of enriched $$^{100}$$Mo for production of medical $$^{rm 99m}$$Tc by $$^{100}$$Mo($$p,2n$$)$$^{rm 99m}$$Tc

Hashimoto, Shintaro; Nagai, Yasuki*

Journal of the Physical Society of Japan, 92(12), p.124202_1 - 124202_11, 2023/12

https://doi.org/10.7566/JPSJ.92.124202
 Times Cited Count：0 Percentile：0(Physics, Multidisciplinary)

$$^{rm 99m}$$Tc, which is a daughter nuclide of $$^{99}$$Mo, is used worldwide for medical imaging. However, there is a problem with the supply of $$^{rm 99m}$$Tc ($$^{99}$$Mo) due to the replacement of aging reactors. A method to produce $$^{rm 99m}$$Tc by irradiating $$^{100}$$Mo with protons using medical cyclotrons has been proposed. In this study, we presented a method to determine individual excitation functions for Mo($$p,x$$)Tc using measured excitation functions for $$^{nat}$$Mo($$p,x$$)Tc. The method was validated by comparing estimated radionuclide purities of $$^{rm 99m}$$Tc in enriched $$^{100}$$Mo samples using the determined excitation functions with measured ones. In this study, we found that the content of $$^{97}$$Mo, $$^{96}$$Mo, and $$^{95}$$Mo should be low in order to produce $$^{rm 99m}$$Tc with high radionuclide purity. The results of this study play an important role in discussion of the required Mo compositions in enriched $$^{100}$$Mo, taking into account the constraints of each facility.

Journal Articles

Medical application of radiohalogenated peptides; Synthesis and ${it in vitro}$ evaluation of F(${it p}$-$$^{131}$$I)KCCYSL for targeting HER2

Sasaki, Ichiro; Watanabe, Shigeki; Ohshima, Yasuhiro; Sugo, Yumi; Yamada, Keiichi*; Hanaoka, Hirofumi*; Ishioka, Noriko

Peptide Science 2015, p.243 - 246, 2016/03

Journal Articles

Economic scale of utilization of radiation in Japan

Yanagisawa, Kazuaki; Kume, Tamikazu; Makuuchi, Keizo

Radioisotopes, 50(11), p.581 - 590, 2001/11

https://doi.org/10.3769/radioisotopes.50.11_581

no abstracts in English

Journal Articles

Economic scale of utilization of nuclear

Takehisa, Masaaki*; Tagawa, Seiichi*; Kashiwagi, Masayuki*; Tominaga, Hiroshi*; Ishikawa, Isamu*; Ooka, Norikazu; Kamada, Toshimitsu*; Hosobuchi, Kazunari*; Makuuchi, Keizo; Takeshita, Hidefumi; et al.

Genshiryoku Riyo No Keizai Kibo; NSA/Commentaries, No.9, 139 Pages, 2001/01

no abstracts in English

Journal Articles

The Economic scale of utilization of radiation in Japan

Yanagisawa, Kazuaki; Kume, Tamikazu; Makuuchi, Keizo

Proceedings of 16th KAIF/KNS Annual Conference, p.259 - 269, 2001/00

no abstracts in English

Journal Articles

The Accelerator production of molybdenum-99

R.M.Lambrecht*; Sekine, Toshiaki; H.Vera-Ruiz*

IAEA-TECDOC-1065, p.75 - 85, 1999/02

no abstracts in English

Journal Articles

Application of molybdenum-99 to nuclear medicine and Its production

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Nihon Genshiryoku Gakkai-Shi, 26(8), p.662 - 670, 1984/00

https://doi.org/10.3327/jaesj.26.662
 Times Cited Count：0 Percentile：0.02(Nuclear Science & Technology)

no abstracts in English

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